Table 3.
Antigenic targets in SARS-CoV-2 IgG antibody-positive participants (as determined by Luminex testing) contrasted by presence or absence of reported symptoms
| Antibody epitope |
Day 1 (positive) | Loss of positivity | Lost to follow-up | New sero-conversions | Epitope changes | Day 28 (positive) | |
|---|---|---|---|---|---|---|---|
| Previously reported symptoms | N and S antigens | 24 | 0 | 2 | 0 | 22 | |
| N antigen only | 3 | 0 | 1 | 0 | 1x N->S swap | 1 | |
| S antigen only | 3 | 1 | 0 | 1 | 4 | ||
| Previously asymptomatic | N and S antigens | 14 | 3 | 0 | 1 | 12 | |
| N antigen only | 29 | 18 | 2 | 0 | 1x N->S swap | 8 | |
| S antigen only | 7 | 4 | 0 | 2 | 6 | ||
| Total | 80 | –26 | –5 | +4 | 53 |
N, nucleocapsid; S, spike.