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. 2021 May;21(5):722–730. doi: 10.1016/S1473-3099(20)30556-9

Table 3.

Diagnostic accuracy of LED-AP and lateral-flow test strip for cryptosporidiosis

LED-AP Lateral-flow test strip
Cryptosporidiosis prevalence 9% (8–12) 10% (8–13)
Sensitivity 88% (79–94) 89% (79–94)
Specificity 99% (98–99) 99% (97–99)
Positive predictive value 88% (79–94) 87·5% (78–93)
Negative predictive value 99% (98–99) 99% (98–99)
Likelihood ratio of a positive test 71·0 (36·9–136·3) 62·6 (32·6–120·4)
Likelihood ratio of a negative test 0·1 (0·1–0·2) 0·1 (0·1–0·2)

Data are point estimates with 95% CI. Cryptosporidiosis was defined as a case of diarrhoea with a positive clinical composite reference standard. Absolute numbers are shown in the appendix (p 10). LED-AP=light-emitting diode fluorescence microscopy with auramine-phenol (AP) staining.