Table 3.
Comparison of safety laboratory parameters in the course of time for per-protocol participants (n = 7)
| Time baseline, mean (SD) | 24 months, mean (SD) | Change | t-test t (df) | p (2-tailed) | Partial η2 | |
|---|---|---|---|---|---|---|
| Calcium, total (mmol/l) | 2.40 (0.09) | 2.45 (0.08) | 2.2% | − 0.97 (6) | 0.37 | 0.14 |
| Calcium albumin corr. (mmol/l) | 2.25 (0.06) | 2.29 (0.06) | 1.8% | − 0.93 (6) | 0.39 | 0.13 |
| Phosphate (mmol/l) | 1.15 (0.16) | 1.12 (0.08) | − 2.7% | 0.61 (5) | 0.57 | 0.07 |
| Creatinine (μmol/l) | 58.1 (12.3) | 60.6 (10.5) | 4.2% | − 0.73 (6) | 0.49 | 0.08 |
| eGFR (crea) (ml/min) | 119.7 (15.0) | 116.7 (14.0) | − 2.5% | 1.04 (6) | 0.34 | 0.15 |
| Vitamine D (μg/l) | 42.7 (12.4) | 34.5 (7.5) | − 19.2% | 3.26 (5) | < 0.05 | 0.68 |
| FSH (IE/l) | 1.84 (4.19) | 1.81 (2.26) | − 1.7% | 0.03 (5) | 0.98 | 0.00 |
| Estradiol (pmol/l) | 98.6 (150.9) | 98.1 (106.8) | − 0.4% | 0.01 (6) | 1.00 | 0.00 |
| Bone specific alkaline phosphatase (μg/l) | 8.30 (2.35) | 13.20 (7.80) | 59.0% | − 1.53 (4) | 0.20 | 0.37 |
| Parathyroid hormone, intact (ng/l) | 41.9 (11.9) | 24.2 (10.7) | − 42.2% | 2.53 (6) | < 0.05 | 0.52 |