Table 3.
Static and dynamic histomorphometry
| Bone parameter‡ | Dam diet | |
|---|---|---|
| Chow (n = 7) | High fat (n = 6) | |
| Bone formation | ||
| Osteoid volume/bone volume (OV/BV; %) | 0.22 ± 0.04 | 0.41 ± 0.09 |
| Osteoid surface/bone surface (OS/BS; %) | 2.88 ± 0.45 | 5.25 ± 1.37 |
| Osteoid thickness (O.Th; μm) | 2.06 ± 0.30 | 2.19 ± 0.24 |
| Osteoblast surface/bone surface (Ob.S/BS; %) | 2.27 ± 0.46 | 3.87 ± 0.76 |
| Osteoblast number/bone perimeter (NOb/BPm; no./100 mm) | 170.13 ± 37.70 | 285.91 ± 58.62 |
| Bone erosion | ||
| Erosion surface/bone surface (ES/BS; %) | 1.51 ± 0.34 | 3.65 ± 0.77* |
| Osteoclast surface (Oc.S/BS; %) | 1.40 ± 0.75 | 3.54 ± 0.89* |
| Osteoclast number/bone perimeter (NOc/BPm; no./100 mm) | 36.13 ± 9.03 | 101.59 ± 27.61* |
| Bone dynamics | ||
| Mineral apposition rate (MAR; μm/day) | 1.29 ± 0.11 | 1.49 ± 0.13 |
| Mineralizing surface/bone surface (MS/BS; %) | 16.54 ± 1.43 | 21.07 ± 2.59 |
| Bone formation rate/bone surface (BFR/BS; mm3/cm2/year) | 7.98 ± 1.32 | 12.02 ± 2.32 |
| Mineralization lag time (Mlt; day) | 0.32 ± 0.06 | 0.41 ± 0.13 |
| Osteoid maturation time (Omt; day) | 1.61 ± 0.20 | 1.56 ± 0.23 |
‡Values are shown as mean ± SEM
*p < 0.05