REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-GFP antibody (FITC)	Abcam	ab6662, RRID:AB_305635
PKC-α	Santa Cruz	sc10800, RRID:AB_2168560
Mouse Cone Arrestin	Milipore	ab15282, RRID:AB_1163387
Human Cone Arrestin (ARRESTIN3)	Novus	NBP1-19629, RRID:AB_2243059
Rhodopsin	Sigma Aldrich	O4886, RRID:AB_260838
M-opsin	Milipore	AB5405, RRID:AB_177456
HuC/HuD	ThermoFisher	A-21271, RRID:AB_221448
mGluR6	Sigma Aldrich	SAB4501324, RRID:AB_10761963
VGLUT	Sigma Aldrich	AB5905, RRID:AB_2301751
CtBP2 (Ribeye)	BD Biosciences	612044, RRID:AB_399431
Calretinin	Abcam	ab702, RRID:AB_305702
Human Nuclei	Millipore	MAB1281, RRID:AB_94090
Peripherin2	Gift from Gabriel Travis	Not Applicable
Synaptophysin	Sigma Aldrich	S5768, RRID:AB_477523
GFAP	DAKO	Z0334, RRID:AB_10013382
c-Myc	Cell Signaling Technology	5605, RRID:AB_1903938
LIN28A	Cell Signaling Technology	3695, RRID:AB_2135033
Nanog	Cell Signaling Technology	4903, RRID:AB_10559205
Oct-4A	Cell Signaling Technology	2840, RRID:AB_2167691
Sox2	Cell Signaling Technology	3579, RRID:AB_2195767
Bacterial and virus strains
AAV.ShH10.L/Mopsin.eGFP	Viral Production Facility, UCL Institute of Ophthalmology	Gonzalez-Cordero et al., 2017
Biological samples
Patient blood	Moorfields Eye Hospital	N/A
Chemicals, peptides, and recombinant proteins
Ames	Sigma Aldrich	A1420
Sodium Bicarbonate	Sigma Aldrich	S6014
L-AP4: L-(+)-2-Amino-4-phosphonobutyric acid	AbCam	ab120002
DNQX: 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione	Sigma Aldrich	D0540
D-AP5: D(−)-2-Amino-5-phosphonopentanoic acid	Sigma Aldrich	A8054
Critical commercial assays
Neurosphere Dissociation Kit (P)	Miltenyi Biotec	130-095-943
P3 Primary Cell 4D-NucleofectorTM X Kit L	Lonza	V4XP-3024
Experimental models: Cell lines
Human: H9 ES cells	WiCell	WA09
Human: CNGB3 iPS cells	This paper	N/A
Experimental models: Organisms/strains
Mouse: Crl:NU(NCr)-Foxn1nu	Charles River	490
Mouse: C3H/HeJ (rd1)	The Jackson Laboratory	000659
Mouse: rd1/Foxn1nu	This paper	N/A
Mouse: C57BL/6J	The Jackson Laboratory	000664
Mouse: Gnat1−/−	Janis Lem, Tufts Medical Centre	Calvert et al., 2000
Recombinant DNA
Plasmid: L-MYC and LIN28 episonal insert (pCXLE-hUL)	Okita et al., 2011	Addgene plasmid #27080
Plasmids: SOX2 and KLF4 episomal insert (pCXLE-hSK)	Okita et al., 2011	Addgene plasmid #27078
Plasmids: OCT3/4 episomal insert (pCXLE-hOCT3/4-shp53-F)	Okita et al., 2011	Addgene plasmid #27077
Software and algorithms
Prism (versions 5 and 7)	GraphPad	GraphPad
ANY-maze	Stoelting Europe	N/A
Adobe Photoshop CS6	Adobe Systems	CS6
ImageJ	NIH	https://imagej.nih.gov/ij/
Multi-Channel Data Suite	Multi-Channel Systems	https://www.multichannelsystems.com/
Offline Sorter V4.4.2	Plexon Inc.	https://plexon.com/
NeuroExplorer V5	Nex Technologies	http://www.neuroexplorer.com/
MATLAB R2019B	The Mathworks	https://www.mathworks.com/
CorelDraw 2020 V22.1.0.517	The Corel Corporation	https://www.coreldraw.com/en/