Table 6. Stratified analysis of ADAMTS gene mRNA in Lauren typing in K–M plotter.
Gene | Lauren typing | Low/high expression cases | HR (95% CI) | P-value |
---|---|---|---|---|
ADAMTS1 | Intestinal | 136/133 | 1.79 (1.23–2.59) | 0.0019 |
Diffuse | 120/120 | 1.3 (0.92–1.83) | 0.13 | |
Mixed | 14/15 | 1.96 (0.6–6.37) | 0.26 | |
ADAMTS2 | Intestinal | 136/133 | 1.55 (1.08–2.23) | 0.017 |
Diffuse | 120/120 | 1.37 (0.97–1.94) | 0.069 | |
Mixed | 14/15 | 0.9 (0.3–2.68) | 0.85 | |
ADAMTS3 | Intestinal | 162/158 | 1.55 (1.13–2.13) | 0.0063 |
Diffuse | 120/121 | 1.35 (0.96–1.9) | 0.088 | |
Mixed | 16/16 | 2.72 (0.92–8.06) | 0.061 | |
ADAMTS4 | Intestinal | 162/158 | 1.55 (1.13–2.13) | 0.0063 |
Diffuse | 120/121 | 1.35 (0.96–1.9) | 0.088 | |
Mixed | 16/16 | 2.72 (0.92–8.06) | 0.061 | |
ADAMTS5 | Intestinal | 134/135 | 1.23 (0.85–1.77) | 0.27 |
Diffuse | 120/120 | 1.54 (1.09–2.18) | 0.013 | |
Mixed | 14/15 | 0.9 (0.3–2.68) | 0.85 | |
ADAMTS6 | Intestinal | 139/130 | 1.81 (1.26–2.62) | 0.0013 |
Diffuse | 121/119 | 1.3 (0.93–1.83) | 0.13 | |
Mixed | 14/15 | 0.74 (0.25–2.24) | 0.6 | |
ADAMTS7 | Intestinal | 147/122 | 2.33 (1.61–3.38) | 4.3e-06 |
Diffuse | 133/107 | 1.4 (0.99–1.96) | 0.054 | |
Mixed | 16/13 | 1.54 (0.51–4.58) | 0.44 | |
ADAMTS8 | Intestinal | 134/135 | 1.42 (0.99–2.05) | 0.057 |
Diffuse | 121/119 | 1.34 (0.95–1.89) | 0.093 | |
Mixed | 14/15 | 2.21 (0.68–7.21) | 0.18 |