The ACS spectrum using the Occlusion MI (OMI) vs. Non-OMI (NOMI) paradigm primarily. The proposed paradigm of MI divides AMI into OMI and NOMI. OMI are those for whom thrombolytics and percutaneous coronary intervention were conceptually designed and indicated, but many OMI do not manifest STEMI criteria. ACS, acute coronary syndrome, MI, myocardial infarction, STEMI, ST-segment elevation MI, OMI, Occlusion MI, NOMI, Non-Occlusion MI.