Table 4.

Risk of post-fracture mortality rate between adults with neurodevelopmental disabilities (NDDs) and adults without NDDs (reference).^*

	With NDDs	ID only	CP only	ASD only
	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
1-month mortality
Model 1	1.27 (0.92, 1.75)	1.62 (1.09, 2.42)	**	**
Model 2	**	**	**	**
3-month mortality
Model 1	1.31 (1.04, 1.64)	1.57 (1.17, 2.10)	**	**
Model 2	1.27 (1.02, 1.59)	1.53 (1.14, 2.05)	**	**
6-month mortality
Model 1	1.50 (1.26, 1.79)	1.82 (1.45, 2.28)	0.98 (0.67, 1.43)	**
Model 2	1.45 (1.22, 1.73)	1.76 (1.41, 2.21)	**	**
12-month mortality
Model 1	1.51 (1.31, 1.75)	1.86 (1.55, 2.25)	0.94 (0.68, 1.29)	1.63 (1.12, 2.38)
Model 2	1.46 (1.27, 1.69)	1.80 (1.49, 2.17)	**	**

ID, intellectual disabilities; CP, cerebral palsy; ASD, autism spectrum disorders; HR, hazard ratio; CI, confidence interval. N=589,659 for all models. Model 1 adjusted for age, sex, race, and US region. Model 2 adjusted for age, sex, race, US region, cardiovascular diseases (i.e., ischemic heart diseases, heart failure, cerebrovascular diseases, and/or hypertension), diabetes (i.e., type 1 or 2, primary or secondary), chronic obstructive pulmonary diseases, and cancer.

^*Number of mortality cases insufficient for analysis for comorbid NDD group.

^**Number of mortality cases insufficient for analysis (model 1, N<20; model 2, N<40).