Figure 1.

Plaquing and kinetic host range of wild-type phages. (A) Comparison of plaquing and kinetic host range over the panel of 110 strains for the wild-type phages. Kinetic host range is lower than plaquing host range for all phages tested. The statistics was calculated by one-way ANOVA for all groups against all groups. **** p < 0,0001; ** p < 0,0021; ns, not significant. (B–D) correlation of OD ratio and EOP for phages 2002, 812 and Remus. The OD ratio represents the ratio of OD 600 after 24 h of phage treated vs. control-treated suspensions; an OD ratio value of 1 indicates that phage-treated bacteria grew to the same OD as the growth control, a value of 0 indicates that bacterial growth was fully suppressed. Opaque lysis (OL) is defined as absence of plaque formation, while at the same time the phage lysate inhibits bacterial growth on a double agar layer plate where it is spotted.