Table 1.

Clinically approved glycosylated ovarian cancer biomarkers.

Marker	Detection Type	Sensitivity (%)	Specificity (%)	Clinical Use	FDA Approval (Year)	Reference
CA 125	Protein concentration	79–94	59–82	Monitoring therapy and relapse	1981	[16,22,23]
HE4	Protein concentration	64–71	85–96	Monitoring therapy and relapse	2008	[12,22,24]
CA 1-9	Protein concentration	50–53	84–97	Monitoring therapy and relapse	2002	[25,26]
ROMA test	Protein concentration	91–94	75–84	Prediction	2011	[18,22,27]
OVA1 test	Protein concentration	77–96	28–35	Prediction	2009	[28,29]
OVA2 (Overa)	Protein concentration	91	69	Prediction	2016	[30]