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. 2021 Apr 1;11(4):643. doi: 10.3390/diagnostics11040643

Table 2.

Serum total N-glycan biomarkers for ovarian cancer. ↑- upregulation, ↓- downregulation.

Glycosylation Trait Regulation in OvCa Reference
high-mannosylation [74,78,81,82,83]
hybrid structures [82]
branching
- mono-, biantennary [78,82]
- triantennary [74,76,78,81,82,84]
- tetraantennary [76,78,81,82]
bisection [76,83]
[85]
Sialylation
- asialylated structures [78]
- sialylated structures [74,76,78,81,86]
- ratio α2-3/α2-6 [73,81,84]