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. 2021 Apr 2;13(4):613. doi: 10.3390/v13040613

Figure 8.

Figure 8

Loss of core protein expression reduced both the intracellular and extracellular levels of HBV envelope proteins in the context of a 1.1 mer construct of genotype A or D. The parental 1.1 mer construct (WT) of genotype A (geno5.4) or genotype D (geno1.2) and the 5 mutants deficient in expressing S, L, and/or core protein were transfected into Huh7 cells. (A) Intracellular L, M, S and core proteins, with GAPDH serving as loading control. (B) Extracellular L, M and S proteins. (C) Extracellular HBsAg with the WT value set at 100. (D) Extracellular preS1 antigen with the WT value set at 100. * p < 0.05; ** p < 0.01.