Table 2.

Effect of the physicochemical properties of NPs on biological performance.

Physicochemical Parameter of NPs	Effect
Shape	Cytotoxicity [50]
	Uptake [51]
	Distribution [52]
Size	Uptake [41]
	Distribution [53]
	Cytotoxicity [41]
Surface charge	Uptake [49]
	Cytotoxicity [49]
	Distribution [54]