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. 2021 Mar 30;13(4):467. doi: 10.3390/pharmaceutics13040467

Table 4.

Physicochemical properties (molecular descriptors) of selected cosurfactants (diols).

Cosurfactants
(Diols)
Chemical Formula C No 1 log P 1 DEC 1 Mwt 1
(g/mol)
C% 1
Ethylene glycol
(1,2-ethanediol)
C2H6O2 2 −1.69 41.4 62.07 38.70
Propylene glycol
(1,2-propanediol)
C3H8O2 3 −1.34 32.0 76.10 47.35
Butylene glycol
(1,2-butanediol)
C4H10O2 4 −0.74 28.8 90.12 53.30
Pentylene glycol
(1,2-pentanediol)
C5H12O2 5 −0.27 18.2 104.15 57.66
Hexylene glycol
(1,2-hexanediol)
C6H14O2 6 0.58 7.70 118.17 60.98

1 C No; carbon atom number, log P; logarithm of partition coefficient in octanol/water, DEC; dielectric constant, Mwt; molecular weight, C%; carbon content weight percent.