Figure 2.

Mitochondrial respiration in intact platelets isolated from diabetic patients treated with statins. ROUTINE respiration (A), LEAK respiration (B), ET capacity (C) R–L net ROUTINE capacity (D), E–L net ET capacity (E), R–L control efficiency (F) and E–L coupling efficiency (G) were determined for three separate groups of diabetic patients (not treated with statins (black column), patients treated with atorvastatin (blue column) and patients treated with rosuvastatin (red column)) and compared to a group of healthy controls (white column). N = 4. Data are expressed as the mean ± SEM of antimycin A–corrected respiration. One–way ANOVA with Bonferroni’s post hoc test was performed. Ns = no statistical significance vs. control. E = electron transfer capacity, ET capacity = electron transfer capacity; L = LEAK respiration; R = ROUTINE respiration.