Figure 1.

Effect of naringin on the hepatic expression of Acyl-CoA oxidase 1 (ACOX1), peroxisome proliferator-activated receptor alpha (PPARα) and glutathione disulfide reductase (GSR) genes relative to control. Graph bars represent mean normalized gene expressions in the livers of animals that received C (no supplemented control), N1 (0.75 g naringin/kg feed) and N2 (1.5 g naringin/kg feed) diets relative to mean normalized expression in the control group. Expression was normalized with the geometric mean of four housekeeping genes. Sample size n = 4. Error bars represent SEM and * denotes statistically significant difference between means (p < 0.05). The effect of naringin on GSR expression is dose-dependent (p-linear = 0.008).