Table 2.
Blood parameters of 12 volunteers at baseline and after 4, 8 and 16 weeks of Lippia citriodora extract treatment.
| BASELINE | 4 WEEKS | 8 WEEKS | 16 WEEKS | ANOVAF (df = 3, 33) |
p Value | |
|---|---|---|---|---|---|---|
| TC | 240.9 ± 10.1 | 236.2 ± 11.4 | 229.2 ± 9.9 * | 227.0 ± 10.2 * | 3.22 | 0.035 |
| HDL-C | 56.6 ± 2.7 | 59.1 ± 2.3 | 62.7 ± 3.3 * | 56.8 ± 3.2 | 4.78 | 0.007 |
| LDL-C | 154.7 ± 9.1 | 147.7 ± 9.2 | 143.7 ± 7.7 * | 144.1 ± 7.6 * | 2.56 | 0.072 |
| TG | 139.8 ± 11.3 | 121.4 ± 12.6 | 111.8 ± 12.3 * | 119.8 ± 13.1 | 2.10 | 0.119 |
| GLU | 100.2 ± 3.1 | 96.3 ± 2.8 * | 88.7 ± 2.3 * | 89.4 ± 2.9 * | 10.11 | 0.002 |
| CPK | 111.7 ± 12.2 | 107.2 ± 14.9 | 107.7 ± 18.9 | 113.7 ± 18.4 | 0.32 | 0.321 |
| AST | 25.7 ± 2.9 | 21.8 ± 1.6 | 23.2 ± 2.8 | 21.0 ± 1.8 | 0.96 | 0.423 |
| ALT | 30.7 ± 5.3 | 24.8 ± 4.2 | 26.9 ± 3.6 | 22.3 ± 1.6 | 1.78 | 0.169 |
| TOS | 13.4 ± 0.9 | 12.9 ± 0.7 * | 12.3 ± 0.6 * | 11.5 ± 0.6 * | 7.42 | 0.012 |
| ROM | 306.5 ± 18.3 | 267.8 ± 7.6 * | 255.3 ± 4.9 * | 271.4 ± 21.3 | 2.99 | 0.069 |
| MDA | 8.1 ± 0.5 | 6.1 ± 0.5 * | 4.4 ± 0.4 * | 3.7 ± 0.2 * | 35.23 | <0.001 |
| FRAP | 0.8 ± 0.04 | 0.9 ± 0.05 * | 0.9 ± 0.06 * | 0.9 ± 0.06 * | 8.13 | 0.002 |
| Vit E | 20.3 ± 1.4 | 23.9 ± 1.2 * | 25.2 ± 1.3 * | 26.2 ± 1.3 * | 27.08 | <0.001 |
| Vit A | 1.2 ± 0.06 | 1.3 ± 0.07 * | 1.4 ± 0.07 * | 1.8 ± 0.14 * | 13.88 | 0.002 |
TC, total cholesterol (mg/dL); HDL-C, high-density lipoprotein cholesterol (mg/dL); LDL-C, low-density lipoprotein cholesterol (mg/dL); TG, triglycerides (mg/dL); GLU, glucose (mg/dL); CPK, creatine phosphokinase (U/L); AST, aspartate transaminase (U/L); ALT, alanine transaminase (U/L); TOS, total oxidant status (µmol H202 Eq/L); ROM, reactive oxygen metabolites (U Carr); MDA, malondialdehyde (nmol/mL); FRAP, ferric reducing ability of plasma (mmol TEAC/L); Vit E, vitamin E (µmol/L); Vit A, vitamin A (µmol/L). Values are mean ± standard deviation; * significantly different compared with baseline (least significant difference).