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. 2021 Mar 26;11(4):503. doi: 10.3390/biom11040503

Table 2.

Effects of anticancer drugs on syndecan-4 expression in different cell models.

Anticancer Drug Cell Type Biological Effects References
Trastuzumab
(Herceptin®)		 Anoikis-resistant endothelial cells Decreases syndecan-4 expression [138]
Panitumumab
(Vectibix®)		 Colon cancer [139]
Bisphosphonate Zoledronic acid (ASCO) Breast cancer Syndecan-4 upregulation [140]