Table 1.
The major features of Crohn’s disease and ulcerative colitis.
| S. No | Characteristics | Crohn’s Disease | Ulcerative Colitis | References |
|---|---|---|---|---|
| 1 | Lesion site | Infects any part of the gastrointestinal tract | Infection limited to the colon | Waugh et al. [33]; Vecchi Brumatti et al. [34]; Younis et al. [35]. |
| 2 | Spreading type | Patchy | Continuous | |
| 3 | Mucosal inflammation | Entire wall and transmural | Limited to the epithelial mucosa | |
| 4 | Frequently involved site | Ileum | Rectum | |
| 5 | Bloody diarrhea | Less common | Very common | |
| 6 | Perianal complications | Common | Rare | |
| 7 | Cytokine inflammation | IFN-y, IL-12, and TNF-α | IL-1, IL-5, and IL-33 |