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. 2021 Mar 30;12(4):507. doi: 10.3390/genes12040507

Figure 5.

Figure 5

Comparison of DEEPGENTM and the AVENIO assay using 13 validated targets with known VAF. (A) Coloured areas represent the fraction of targets detected by DEEPGENTM (violet) and AVENIO (light grey) at 0.125%, 0.25% and 0.5% VAF. (B) Specificity, sensitivity, PPV, NPV and accuracy for DEEPGENTM and AVENIO assays for each tested VAF. (C) Overview of all 13 overlapping targets (at 0.125% VAF) with their measured variant frequencies from the AVENIO and DEEPGENTM assays.