Table 2.

Exercise-induced changes in tumor infiltration of macrophages (M), neutrophils (N), natural killer cells (NK), total T lymphocytes (CD3⁺), cytotoxic T lymphocytes (CD8⁺), T helper lymphocytes (CD4⁺), and regulatory T lymphocytes (Tregs) and their impact on tumor growth in mice.

No	Study	Tumor	Exercise Duration	Tumor Infiltration							Tumor Growth
				M	N	NK	CD3+	CD8+	CD4+	Tregs
10	Abdalla et al., 2014	Drug DMBA	8 weeks	↑(M1)							↓
12	Zielinski et al., 2004	EL-4 lymphoid	2 weeks	↓	↓		↑				↓
13	Almeida et al., 2009	Ehrlich tumor	6 weeks	↓	↓						↓
14	Rundqvist et al., 2020	I3TC cells	10 weeks	—	—	—		↑	—		↓
15	McClellan et al., 2014	intestine tumor	12 weeks	↓				↑		↓	↓
22	Pedersen et al., 2016	B16 melanoma	6 weeks			↑	↑				↓
		B16 lung *	6 weeks			↑	—				↓
23	Wang et al., 2020	4T1 breast	44 days			↑					↓
33	Hagar et al., 2019	4T1 breast	8 weeks							↓(CD8/ FoxP3)	↓
34	Wennerberg et al., 2020	4T1 breast	22 days					—(↑CD56)			↓
35	Shamsi et al., 2019	4T1 cells	12 weeks						—		↓

DMBA: dimethylbenz(a)anthracene, M1: macrophages 1, ↑: increase, ↓: reduction, —: no change, * metastatic tumor.