Table 4.

Association of FGF21 with eating behavior and food and drug craving in the Sorbs.

Dependent Variables	FGF21 (Unadjusted)		FGF21 (Adjusted for Age, Sex, BMI)
Linear regression
	β	p	β	p	n
Disinhibition	−0.152	0.001	−0.158	2.170 × 10−4	465
Hunger	−0.061	0.184	−0.052	0.260	465
Restraint	0.066	0.153	0.045	0.318	465
Packyears	0.239	6.800 × 10−5	0.111	0.030	268
Generalized linear model
	OR	p	OR	p	n
Alcohol consumption	1.315	1.300 × 10−5	1.281	1.510 × 10−4	768
Coffee consumption	0.872	0.029	0.800	0.001	761
Binary logistic regression
	OR	p	OR	p	n
Smoker (yes/no)	1.341	7.200 × 10−5	1.394	6.700 × 10−5	780

Prior to statistical analysis the variables packyears, serum FGF21, BMI and age were ln-transformed. Assessments were done using linear regression for eating behavior and packyears, generalized linear model for alcohol and coffee consumption and binary logistic regression for smoking status. A p-value 0.05 was considered to be significant and was highlighted in bold. FGF21 = fibroblast growth factor 21; BMI = body-mass-index; OR = odds ratio; β = regression coefficient; p = p-value; n = number of subjects.