Table 10.

Association of representative SNPs for each LD-group with food and drug craving in the Sorbs cohort.

		LD 1	LD 2	LD 3	LD 4	LD 5	LD 6	LD 7	LD 8	n
Disinhibition	β	−0.014	−0.295	0.124	−0.228	−0.242	0.034	−0.148	0.014
	s.e.	0.259	0.152	0.190	0.154	0.167	0.314	0.287	0.186	572
	p	0.957	0.053	0.514	0.141	0.148	0.915	0.608	0.942
Hunger	β	−0.070	−0.241	−0.065	−0.251	−0.388	0.154	−0.027	−0.118
	s.e.	0.263	0.155	0.193	0.157	0.170	0.319	0.292	0.190	572
	p	0.790	0.120	0.739	0.110	0.023	0.629	0.927	0.533
Restraint	β	−0.554	−0.089	0.017	−0.256	−0.176	0.176	0.544	−0.178
	s.e.	0.447	0.264	0.329	0.267	0.290	0.543	0.497	0.322	572
	p	0.216	0.736	0.958	0.339	0.544	0.746	0.274	0.580
Smoking yes/no	OR	1.188	1.105	1.292	1.100	1.024	1.054	1.058	1.299
	s.e.	0.173	0.100	0.123	0.103	0.110	0.210	0.190	0.121	958
	p	0.321	0.320	0.038	0.364	0.827	0.803	0.767	0.030
Cigarettes (Packyears)	β	0.021	0.140	0.070	0.145	0.072	−0.204	0.051	0.073
	s.e.	0.146	0.086	0.098	0.088	0.095	0.182	0.151	0.098	323
	p	0.883	0.105	0.476	0.102	0.450	0.262	0.734	0.455
Coffee	OR	0.904	1.057	0.973	1.045	1.031	0.953	0.979	1.030
	s.e.	0.160	0.092	0.114	0.094	0.101	0.194	0.175	0.111	931
	p	0.530	0.551	0.808	0.638	0.763	0.804	0.903	0.788
Alcohol	OR	1.434	1.010	1.150	1.051	1.027	1.204	0.973	0.982
	s.e.	0.198	0.114	0.144	0.117	0.126	0.238	0.230	0.142	952
	p	0.069	0.928	0.332	0.671	0.833	0.436	0.906	0.900

The presented associations are given for the representative SNP within each LD-group. Prior analysis, all variables were ln-transformed except smoking, alcohol and coffee consumption, scores of eating behavior and sex. p-values were adjusted for: sex, age, BMI and a p-value 0.05 was considered to be significant and highlighted in bold. Linear regression including all subjects was conducted. The variables alcohol, coffee and smoking have been analyzed using ordinal regression and including all subjects. LD = linkage disequilibrium; OR = odds ratio; p = p-value; β = regression coefficient; s.e. = standard error; n = number of subjects.