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. 2021 Apr 3;9(4):756. doi: 10.3390/microorganisms9040756

Table 1.

A chemical library targeting viral enzymes.

No Name of Compound Molecular Weight Molecular Formula CAS Number Reference
1-1 Acyclovir 225.20 C8H11N5O3 59277-89-3 [23]
1-2 Cidofovir 279.19 C8H14N3O6P xH2O 113852-37-2 [24]
1-3 Ganciclovir 255.23 C9H13N5O4 82410-32-0 [25]
2-1 Favipiravir 157.10 C5H4FN3O2 259793-96-9 [26]
2-2 Remdesivir 291.27 C12H13N5O4 1809249-37-3 [27,28]
2-3 Sofosbuvir 529.45 C22H29FN3O9P 82-93-9 [29]
3-1 Raltegravir 482.51 C20H20FKN6O5 871038-72-1 [30]
4-1 Abacavir 225.20 C8H11N5O3 188062-50-2 [31]
4-2 Emtricitabine 247.25 C8H10FN3O3S 143491-57-0 [32]
4-3 Entecavir 277.28 C12H15N5O3 142217-69-4 [33]
4-4 Lamivudine 229.26 C8H11N3O3S 134678-17-4 [31]
4-5 Ribavirin 244.20 C8H12N4O5 36791-04-5 [31]
4-6 Tenofovir 305.23 C9H14N5O4P H2O 206184-49-8 [32]
4-7 Zidovudine 267.24 C10H13N5O4 30516-87-1 [34]
5-1 Darunavir 547.66 C27H37N3O7S 206361-99-1 [35]
5-2 Indinavir 613.79 C36H49N5O8S 180683-37-8 [30]
5-3 Lopinavir 628.80 C37H48N4O5 192725-17-0 [36]
5-4 Nafamostat mesylate 539.58 C19H17N5O2 2CH4O3S 82956-11-4 [37]
6-1 Cobicistat 776.0 C40H53N7O5S2 1004316-88-4 [38]
6-2 Ritonavir 720.94 C37H48N6O5S2 155213-67-5 [27,39]
6-3 Sildenafil 666.70 C22H30N6O4S C6H8O7 171599-83-0 [40]
6-4 Tadalafil 389.40 C22H19N3O4 171596-29-5 [41]
6-5 Chloroquine 515.86 C18H26ClN3 2H3PO4 50-63-5 [42]
6-6 Hydroxychloroquine 433.95 C18H26ClN3O H2SO4 747-36-4 [42]

DNA polymerase inhibitors, 1-1~3; RNA polymerase inhibitors, 2-1~3; integrase inhibitors, 3-1; reverse transcriptase inhibitors, 4-1~7; protease inhibitors, 5-1~4; others, 6-1~4.