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. 2021 Mar 30;9(4):358. doi: 10.3390/biomedicines9040358

Figure 2.

Figure 2

Preventive effect of A. borbonica (A. b) 25 mg/kg on renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction (UUO) in mice. (A) Experiment design: black arrows indicate daily gavage with 25 mg/kg A. b. (B) Renal tubulointerstitial fibrosis highlighted with the Sirius red staining, arrows indicate interstitial fibrosis. (C) qPCR analyses of mRNA–macrophage infiltration (F4/80) and myofibroblasts (α-Sma); n = 5 per group. * p < 0.05 compared to Sham; $ p < 0.05 compared to UUO + Veh. Scale bar =100 μm.