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. 2021 Mar 29;13(4):1125. doi: 10.3390/nu13041125

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the experimental set up: (A) Short-term incubations (part 1) to assess interindividual variability, using fecal samples from six donors D1–D6 (48 h); (B) Long-term SHIME^® study (part 2) using the selected fecal samples (D2 and D4) from the screening of two donors (4 weeks). AOB = antioxidant blend; XOS = xylooligosaccharides; FOS = fructo-oligosaccharides; SFCA = short-chain fatty acid; ST/SI = stomach/small intestine; PC = proximal colon; DC = distal colon; SHIME^® = simulator of the human intestinal microbial ecosystem.