Table 2.
Average microbial abundances of the 30 most abundant OTUs (log(cells/mL)) as detected via quantitative 16S rRNA gene-targeted Illumina sequencing of AOB, XOS and FOS versus a blank control during 2 weeks of treatment (n = 4) for donor 2. Statistically significant differences between the control and treatments are indicated in bold (p < 0.05). PC = proximal colon; DC = distal colon; CTRL = control; AOB = antioxidant blend; XOS = xylooligosaccharides; FOS = fructooligosaccharides.
| Phylum | Family | OTU | Related to | PC | DC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CTRL | AOB | XOS | FOS | CTRL | AOB | XOS | FOS | ||||
| Actinobacteria | Bifidobacteriaceae | OTU 01 | Bifidobacterium adolescentis | 8.39 | 8.37 | 8.74 | 7.79 | 8.05 | 8.16 | 8.67 | 7.75 |
| OTU 07 | Bifidobacterium longum | 8.16 | 8.44 | 8.21 | 8.27 | 7.87 | 8.34 | 8.18 | 8.14 | ||
| Bacteroidetes | Bacteroidaceae | OTU 04 | Bacteroides dorei | 8.04 | 8.11 | 8.46 | 8.61 | 8.19 | 8.54 | 8.41 | 8.31 |
| OTU 05 | Bacteroides fragilis | 8.45 | 7.90 | 7.65 | 5.62 | 8.66 | 7.89 | 7.93 | 7.53 | ||
| OTU 11 | Bacteroides ovatus | 6.08 | 5.89 | 6.93 | 7.31 | 7.44 | 6.90 | 7.83 | 8.93 | ||
| OTU 13 | Bacteroides uniformis | <LOQ | <LOQ | <LOQ | <LOQ | 6.37 | 6.22 | 7.16 | 6.17 | ||
| OTU 08 | Bacteroides xylanisolvens | 8.34 | 8.02 | 7.73 | 7.45 | 8.05 | 7.59 | 8.22 | 8.36 | ||
| OTU 20 | Prevotella salivae | 7.04 | 7.52 | 7.26 | 7.31 | 6.48 | 7.02 | 7.16 | 7.15 | ||
| Firmicutes | Erysipelotrichaceae | OTU 17 | Clostridium innocuum | <LOQ | <LOQ | <LOQ | <LOQ | 5.46 | 7.07 | <LOQ | 5.50 |
| Lachnospiraceae | OTU 03 | Clostridium clostridioforme | 8.38 | 8.01 | 8.20 | 8.40 | 8.62 | 8.28 | 8.36 | 8.51 | |
| OTU 06 | Lachnoclostridium sp. | 7.80 | 7.68 | 6.74 | 8.08 | 6.27 | 6.56 | 6.07 | 6.85 | ||
| OTU 16 | Blautia wexlerae | 5.84 | 7.68 | 5.52 | 8.34 | 7.16 | 7.78 | 6.71 | 8.39 | ||
| OTU 14 | Eubacterium rectale | <LOQ | <LOQ | <LOQ | <LOQ | 7.11 | 6.35 | 7.65 | 7.88 | ||
| OTU 30 | Clostridium sp. | <LOQ | <LOQ | <LOQ | <LOQ | 6.59 | 7.45 | 6.83 | 6.68 | ||
| OTU 34 | Lachnospiraceae spp. | <LOQ | <LOQ | <LOQ | <LOQ | 6.66 | 6.59 | 7.63 | 7.60 | ||
| OTU 26 | Blautia coccoides | <LOQ | <LOQ | <LOQ | <LOQ | 7.83 | 7.32 | 7.72 | 7.20 | ||
| OTU 28 | Lachnospiraceae spp. | 6.77 | 6.89 | 7.43 | 6.43 | 6.91 | 7.03 | 7.54 | 6.95 | ||
| Lactobacillaceae | OTU 12 | Pediococcus acidilactici | 7.62 | 7.76 | 7.70 | 6.79 | 7.62 | 7.37 | 7.93 | 7.23 | |
| Ruminococcaceae | OTU 18 | Subdoligranulum sp. | <LOQ | <LOQ | <LOQ | <LOQ | <LOQ | 7.16 | <LOQ | 7.52 | |
| OTU 24 | Faecalibacterium prausnitzii | <LOQ | <LOQ | <LOQ | <LOQ | 6.42 | 7.52 | 6.37 | 7.72 | ||
| Veillonellaceae | OTU 09 | Anaeroglobus geminatus | 7.76 | 7.83 | 7.19 | 7.12 | 7.31 | 7.62 | 8.10 | 7.91 | |
| OTU 22 | Dialister invisus | 7.26 | 7.22 | 7.17 | 7.76 | 7.10 | 6.91 | 7.00 | 7.44 | ||
| Fusobacteria | Fusobacteriaceae | OTU 33 | Fusobacterium nucleatum | <LOQ | <LOQ | <LOQ | <LOQ | 7.27 | <LOQ | 7.21 | 7.11 |
| Verrucomicrobia | Akkermansiaceae | OTU 15 | Akkermansia muciniphila | <LOQ | <LOQ | <LOQ | <LOQ | 8.29 | 8.15 | 8.13 | 8.16 |