Figure 3.

The snRNA-seq of human postmortem brain tissues in studies of PD. (a,b) Use of SN and cortex tissues derived from five healthy individuals. Reprinted from [30], Copyright 2020, Devika Agarwal et al. (a) UMAP (colored by cell type) and (b) correlation heatmap depicting hierarchical clustering with Pearson correlation as distance metric. (c–e) Use of SN tissues derived from seven healthy individuals. Reprinted from [32], Copyright 2019, with permission from Elsevier. UMAP plots colored by (c) donor and (d) cell type. (e) Violin plots depicting expression of PD-related genes across the identified cell types.