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Extracted ion chromatograms of HPLC-MS analysis for all metabolites obtained after 30-min incubations of 0.05 mM (A) C-2028, (B) C-2045 and (C) C-2053 with 1 mg/mL of P4503A4 and P4502C19 isoenzymes. The 2 mM NADPH was applied as the cofactor.
