. 2021 Apr 1;14(4):317. doi: 10.3390/ph14040317

Table 3.

The structures proposed for main metabolites of UAs formed with P4503A4 and 450P2C19 isoenzymes (1 mg/mL P450 and 2 mM NADPH cofactor) on the basis of their ESI-MS and ESI-Q-TOF-MS (ElectroSpray Ionistaion-Quadrupole-Time of Flight-Mass Spectrometry) analyses.

Metabolite	HPLC Retention Time [min]	ESI-MS m/z	ESI-Q-TOF-MS m/z
M1²⁸	15.06	556.25 [M + H-30]⁺	556.2799 [M+H-30]⁺
M2²⁸	18.10	568.25 [M+H-18]⁺	568.2458 [M+H-18]⁺
M3²⁸	18.42	572.25 [M+H-14]⁺	572.2403 [M+H-14]⁺
M4²⁸	15.64	307.25	307.1545
M1⁴⁵	14.10	586.25 [M+H-30]⁺	586.2928 [M+H-30]⁺
M2⁴⁵	18.40	598.25 [M+H-18]⁺	598.2554 [M+H-18]⁺
M1⁵³	16.23	570.25 [M+H-30]⁺	570.2975 [M+H-30]⁺
M2⁵³	20.50	582.25 [M+H-18]⁺	582.2612 [M+H-18]⁺
M3⁵³	20.16	586.25 [M+H-14]⁺	586.2563 [M+H-14]⁺