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Histological images of immunostaining for articular cartilage (A). Gremlin-1 showed a decreased positive cell rate in the CAJM group (B), and MMP-13 showed a decreased positive cell rate in the CAJM and CAJM + Ex groups compared to that in the ACL-T group (C) (each group, n = 8). ACL-T, anterior cruciate ligament transection group; CAJM, controlled abnormal joint movement; Ex, treadmill exercise. Scale bar: 100 μm.
