Skip to main content
. 2021 Apr 1;9(4):324. doi: 10.3390/vaccines9040324

Table 1.

Summary of study key parameters and results.

Dose Group. Number of Mice Dose Per Mouse Infection Neutral. Ab Titer Viral Load Log10 Alveolar Score Blood Vessel Score
Normal Mild Mod. Normal Mild Mod.
High 10 5 µg 105TCID50/50 µL 1024 * 0+/−0 * 2 7 1 6 4 0
Medium 10 1 µg >1024 * 0+/−0 * 1 7 2 3 7 0
Control 8 - <8 6+/−0.22 0 2 6 3 5 0

* p << 0.001 compared to control. Listed from left to right are, for each dose group, number of animals per group; vaccine dose per animal per shot; viral infection dose per animal; titers of neutralizing antibodies with <8 being below the lower limit and >1024 being higher than upper limit of quantification; viral load given as log10 of the viral particle count; and the number of animals per lung lesion score (see Figure 1 for definition of scores).