Figure 1.

Cluster and homology analysis of human and mouse LOX families. Homology analysis of LOX families between humans and mice. (A) The evolutionary tree of the LOX family in humans and mice. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1000 replicates) was shown next to the branches. (B) Structure analyses of mouse LOX family members. LTQ, lysyl-tyrosyl-quinone; CRL, cytokine receptor-like. SRCR, scavenger receptor cysteine-rich. (C) The sequence alignment of mouse LOXL4 and human LOXL4. (D) The sequence alignment of mouse LOXL4 lysyl oxidase (LO) domain and mouse LOX LO domain. *, indicates the number of amino acids, which is marked every twenty amino acids.