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. 2021 Apr 16;31(3):214–226. doi: 10.1089/cap.2020.0148

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© Azmi Nasser et al. 2021; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 4. — Link functions for WFIRS-P scores and CGI-S/CGI-I Levels. Children (blue line) and adolescents (red triangles) are from the present analysis in pediatric patients treated with SPN-812 or placebo. Shaded bands represent 95% confidence intervals by age group. (A) Baseline WFIRS-P Total Average scores and CGI-S levels. (B) WFIRS-P Total Average scores absolute change from baseline and CGI-I levels at the end of study. (C) WFIRS-P Total Average scores percent change from baseline and CGI-I levels at the end of study. CGI, Clinical Global Impressions; CGI-I, CGI-Improvement; CGI-S, CGI-Severity; WFIRS-P, Weiss Functional Impairment Rating Scale-Parent.