Table 3.
Proportion of Participants Reaching the Responder Definition from Screening to Week 3
| Responder definition (−9)a | |
|---|---|
| DR/ER-MPH, n (%) | 42 (53.2) |
| Placebo, n (%) | 23 (29.9) |
| Difference (%) | 23.3 |
| 95% confidence interval | 8.0–38.5 |
| p-Valueb | 0.003 |
a
Responder definition was estimated as the mean MCT for the following anchors: ≥30% decrease in ADHD-RS-IV (−6) and CGI-I ≤2 (−12).
b
p-Value from chi-square test.
ADHD-RS-IV, attention-deficit/hyperactivity disorder rating scale-IV; CGI-I, Clinician Global Impression—Improvement; DR/ER-MPH, delayed-release and extended-release methylphenidate; MCT, meaningful change threshold.