Table 4.
Effect of SEDDS excipients on the complex stability. The complexation efficiency (CE %) after interactions with a SEDDS excipient is reported relative to the control where no SEDDS excipient was added (CE = 100%).
| SEDDS Excipient | CE (%) | |
|---|---|---|
| DDAB-OND | DOTAP-OND | |
| Citrem | 97.3 ± 0.2 *** | 97.7 ± 0.2 *** |
| LPC | 100.0 ± 0.2 | n.d. |
| Captex 300 | 100.3 ± 0.1 | 100.1 ± 0.1 |
| Labrasol | 100.5 ± 0.2 | 100.2 ± 0.1 |
| Maisine CC | 100.8 ± 0.1 | 100.4 ± 0.1 |
| Peceol | 100.2 ± 0.4 | 100.3 ± 0.1 |
*** statistically significant difference relative to a control with added lipid. Results are presented as mean ± SD (n = 3). n.d. = not determined.