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. 2021 Mar 29;11(4):439. doi: 10.3390/brainsci11040439

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Representative images from one rat of the control group. The volume of the infarction was manually measured on the diffusion-weighted imaging (DWI) map. To measure the perfusion indices, the region of interest (ROI) was manual drawing in the infarcted hemisphere on the relative cerebral blood volume (rCBV) image. A mirror ROI on the contralateral healthy hemisphere was then generated automatically by the software. The ROIs were applied to other perfusion maps to measure other perfusion indices.