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Flow diagram revealing the number of plasma, sequences and patients on various cART regimens. Seqs, sequences; DTG, dolutegravir; RAL, raltegravir, cART, combination antiretroviral therapy; INSTI, integrase strand transfer inhibitors. VS-Int, ViroSeqTM HIV-1 Integrase RUO Genotyping kit Celera Corporation, USA; IH-Int, inhouse integrase assay. * Seqs clustering together with high bootstrap (>95) but being from different individuals.
