Table 2.
In vitro activity of eight antifungal agents and chlorhexidine digluconate against the Fusarium strains of the described fungal keratitis cases.
| MIC % (mg/L) | MIC mg/L | MEC mg/L | |||||||
|---|---|---|---|---|---|---|---|---|---|
| CHX | AMB | ITC | VCZ | POS | ISA | ANI | CAS | MCF | |
| F. proliferatum (case 1) | 0.0008 (4) | 0.5 | >16 | 4 | 1 | 16 | >16 | >32 | >2 |
| F. falciforme (case 2) | 0.0064 (32) | 2 | >16 | >16 | 16 | 16 | 16 | >32 | >2 |
| F. verticillioides (case 3) | 0.0032 (16) | 2 | >16 | 2 | 0.5 | 16 | 16 | >16 | >2 |
| F. oxysporum (case 4) | 0.0004 (2) | 1 | ND | >16 | >16 | ND | ND | >32 | ND |
MIC, minimum inhibitory concentration; MEC, minimum effective concentration; CHX, chlorhexidine; AMB, amphotericin B; ITC, itraconazole; VCZ, voriconazole; POS, posaconazole; ISA, isavuconazole; ANI, anidulafungin; CAS, caspofungin; MCF, micafungin; ND: not determined.