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. 2021 Mar 30;10(4):539. doi: 10.3390/antiox10040539

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MJe diminished both generation of reactive oxygen species (ROS) and fall of mitochondrial membrane potential (ΔΨm) induced by 6-OHDA. (A) ROS accumulation was measured using the fluorescent probe DCFH-DA. (B) ΔΨm was assessed using the cationic fluorochrome R123. Results are reported as percentage of the levels detected in untreated cells. Data are displayed as the mean ± SEM of three experiments in triplicate (N = 9). °° p < 0.01 and °°° p < 0.001 vs. ctrl; * p < 0.05 and *** p < 0.001 vs. 6-OHDA 50 µM.