Figure 4.

Independent components discriminant analysis proportions plot calculated after source signal extraction for the data obtained by HILIC chromatography and corresponding F-value associated with the Wilks’ lambda characterizing the discrimination of the predefined groups: (A) to discriminate the fat content. Separation of the HD groups from the CD-group based on IC1, IC2 and IC2; (B) to discriminate the protein content diet sequences, poor separation of the NP-HP group with HP-NP group based on IC2, IC3 and IC4; (C) to discriminate the diets, whatever the intervention period. Partial separation of the HP, NP and CD-groups based on IC1, IC2 and IC3. CD: control diet; HD: high-fat, hypercaloric diet whatever the protein content of the diet; NP-HP: NPHD at P1 and HPHD P2 period; HP-NP: HPHD at P1 and NPHD P2 period; HP: HPHD at either P1 or P2 period; NP: NPHD at either P1 or P2 period; QC: quality controls.