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Neutralizing anti-HMGB1 antibodies reduced the auditory brainstem response (ABR) threshold shift in mice with noise-induced hearing loss. The ABR was recorded from one ear in each animal. The results are expressed as the mean ± SEM (n = 5 [refers to 5 measured ears from 5 different animals]). * p < 0.05; ** p < 0.01; SEM = standard error of the mean.
