SERS platforms based on transparent polymers: (a) AuNRs/PDMS platform: schematic illustration of the preparation of AuNRs/PDMS substrate, SERS spectra of aqueous CV at various concentration, and SERS spectra of CV acquired by applying the nanocomposite film on the fish scale and then illuminating from the backside with a 785 nm laser. Adapted with permission from [101]. Copyright (2017) American Chemical Society. (b) AuNSs/PDMS microfluidic channel for SERS: Schematic illustration of the fabrication process of depicting the final device coupled with the Raman fiber probe; Raman spectra of aβ-42-peptide against buffer solution for Citrate-AuNSs substrates, and LA-AuNSs-PDMS; finally, a comparison of the background-subtracted Raman ‘fingerprint’ spectral region of aβ-42-peptide between bare PDMS, Citrate-AuNSs, LA-AuNSs substrates. Adapted with permission from [50]. Copyright (2020), IOP Publishing Ltd.