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. 2021 Apr 1;9(4):738. doi: 10.3390/microorganisms9040738

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Serotype-specific distribution of CSF+ pneumococcal meningitis in the mature PCV10/13 period. Serotypes are colored by the lowest valency PCV product they are included in. The “x” in the PCV legend represents the extra serotypes included in that product relative to the next lower product (i.e., PCV13x includes serotypes 3, 6A, and 19A not in PCV10). PCV13 is Pfizer’s Prevnar13/Prevenar13; PCV10 is GSK’s Synflorix. Serotype 6C is colored separately because, although it is not included in any product, it is covered through cross-protection with PCV13-type serotype 6A [24]. Morocco and Bulgaria were not included in the PCV10 distribution due to serotyping limitations. * Serotype distribution for PCV13 sites is modeled output for the top 25 serotypes based on a pooled ranking plus serotype 1. Serotype distribution for PCV10 sites is from pooling cases across sites.