Table 4.

Correlations between MRI measures and patient outcome assessments

Imaging measure	Region	Assessment	Direct		Partial
			r	P	r	P
ADC	Genu of CC	Number series z-score	0.40	0.048	0.44	0.035
	Cortical GM	Backward digit z-score	0.42	0.035	0.46	0.027
FA	Caudate	Emotional RPQ	−0.46	0.018	−0.48	0.019
	Caudate	Category fluency z-score	−0.43	0.038	−0.43	0.043
	Caudate	Word list recall z-score	−0.52	0.007	−0.50	0.016
	Frontal WM	RPQ 3	−0.50	0.010	−0.46	0.029
	Frontal WM	Somatic RPQ	−0.44	0.023	−0.45	0.031
	Pallidus	Cognitive RPQ	0.39	0.048	0.40	0.056
	Posterior WM	Short-delay word list recall z-score	0.49	0.013	0.48	0.020
ROI-based TSC	Genu of CC	Total RPQ	0.43	0.027	0.40	0.052
	Genu of CC	RPQ 13	0.44	0.023	0.41	0.046
	Genu of CC	Cognitive RPQ	0.41	0.032	0.46	0.023
Linear regression of TSC	GM	BTACT composite z-score	0.38	0.059	0.55	0.005
	GM	Short-delay word list recall z-score	0.40	0.045	0.38	0.066
	GM	Number series z-score	0.45	0.020	0.48	0.017
	GM	Word list recall z-score	0.43	0.026	0.47	0.019
	WM	BTACT composite z-score	0.46	0.018	0.41	0.045
	WM	Backward counting z-score	0.40	0.045	0.40	0.050
	WM	Number series z-score	0.45	0.020	0.48	0.018

Direct and partial Spearman correlations (r) and P values for the association of each imaging measure with the z-scores from the Brief Test of Adult Cognition by Telephone (BTACT) and Rivermead Post-Concussion Symptoms Questionnaire (RPQ) without (direct) and with (partial) adjustment for the elapsed time from injury to imaging. Total/composite scores are highlighted in italic bold. Shown are only those associations in which at least one of the direct and the partial correlations was statistically significant (bold).

CC = corpus callosum; GM = grey matter; WM = white matter; ADC = apparent diffusion coefficient; FA = fractional anisotropy; TSC = total sodium concentration.