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. 2021 Mar 30;9(4):357. doi: 10.3390/biomedicines9040357

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Viability of HL60/MDR cells treated for 48 h by doxorubicin (DOXO) at a concentration of 1 μM in the presence or absence of the flavonoids (10, 9, 7, 6 and 5) or verapamil (VERA), all at a concentration of 20 μM. The viability of cells after treatment with doxorubicin alone was compared with viability after treatment with doxorubicin in combination with the flavonoid or verapamil used as a positive control. The data show the means ± SD of at least three independent experiments. (* p < 0.05; ** p < 0.005).