Table 3.
The effect of omega-3 and omega-6 FA on TXB, BDNF, HCy, and vitamin D in patients with depressive disorder.
| Parameter | Om3 Group (n = 29) | Om6 Group (n = 29) | p-Values between Om3 and Om6 Groups | |||||
|---|---|---|---|---|---|---|---|---|
| Week 6 | Week 12 |
p-Value to Baseline * |
Week 6 | Week 12 |
p-Value to Baseline * |
Week 6 | Week 12 | |
| TXB (pg/mL) |
318.3 ± 173.7 | 291.7 ± 140.0 | 0. 037 | 425.9 ± 275.5 | 406.3 ± 180.1 | ns | 0.091 | 0.024 |
| BDNF (ng/mL) |
827.2 ± 441.3 | 824.7 ± 416.7 | 0.040 | 683.4 ± 413.9 | 592.5 ± 220.2 | ns | ns | 0.011 |
| HCy (µmol/L) | 13.6 ± 9.3 | 11.6 ± 8.1 | ns | 11.4 ± 5.7 | 11.3 ± 7.2 | ns | ns | ns |
| Vitamin D (ng/mL) | 18.7 ± 7.8 | 20.9 ± 8.3 | ns | 17.8 ± 5.2 | 21.7 ± 8.5 | ns | ns | ns |
TXB = thromboxane B, BDNF = brain-derived neurotrophic factor, HCy = homocysteine, p = statistical significance; * significance after 12 weeks of supplementation; ns = not significant, n = number of individuals in the group, the numbers in the bold are statistically significant.