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. 2021 Mar 30;11(4):883. doi: 10.3390/nano11040883

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Impact of MWCNTs on the chemokine signaling network in macrophage-like cells. (A) The figure depicts the transcriptomics results for MWCNT-exposed (25 µg/mL) THP-1 cells at 24 h. The color coding shows upregulated (red) and downregulated genes (green). Data were analyzed and visualized by using the IPA software tool (Qiagen, Inc., www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis). (B) Western blot assay for the expression of NLRP12 in THP-1 cells exposed or not to MWCNTs (25 µg/mL) for 24 h. GAPDH was included as a loading control.