Figure 1.

Average electrically evoked action potentials of Nitellopsis obtusa internodal cells in artificial pond water (APW) with standard conditions and after exposure to different inhibitors of human two-pore channels (TPCs): (a) APs after exposure to 300 µM verapamil. The upper insert represents spontaneous APs after electrical excitation (indicated by arrows) and subsequent complete depolarization of membrane potential; (b) APs after exposure to 75 µM NED-19; (c) APs after exposure to 100 µM tetrandrine. Horizontal bars indicate SD of t_dep and t_rep; vertical—resting potential (RP), excitation threshold (E_th), and peak potential V_max for each drug n = 6−7.