Table 1.
APW | Verapamil 300 µM | APW | NED-19 75 µM | APW | Tetrandrine 100 µM | |
---|---|---|---|---|---|---|
RP (mV) | −210 ± 11 (n = 7) |
−140 ± 62 (n = 7)* |
201 ± 15 (n = 7) |
−155 ± 33 (n = 7)* |
−203 ± 21 (n = 6) |
−165 ± 44 (n = 6)* |
Eth (mV) | −101 ± 12 (n = 7) |
−73 ± 35 (n = 7)* |
−108 ± 9 (n = 7) |
−81 ± 20 (n = 7)* |
−78 ± 18 (n = 6) |
−80 ± 17 (n = 6) |
Vmax (mV) | 36 ± 14 (n = 7) |
37 ± 24 (n = 7) |
35 ± 10 (n = 7) |
27 ± 25 (n = 7) |
30 ± 4 (n = 6) |
32 ± 6 (n = 6) |
Ath (mV) | 137 ± 21 (n = 7) |
110 ± 52 (n = 7) |
143 ± 10 (n = 7) |
107 ± 31 (n = 7)* |
107 ± 18 (n = 6) |
112 ± 18 (n = 6) |
ARP (mV) | 254 ± 14 (n = 7) |
178 ± 79 (n = 7)* |
231 ± 17 (n = 7) |
181 ± 33 (n = 7)* |
233 ± 21 (n = 6) |
197 ± 42 (n = 6) |
tdep (s) | 0.8 ± 0.1 (n = 7) |
1.6 ± 0.7 (n = 7)* |
0.9 ± 0.1 (n = 7) |
1 ± 0.2 (n = 7) |
1.3 ± 0.2 (n = 6) |
1.9 ± 0.3 (n = 6)* |
trep (s) | 2.6 ± 0.7 (n = 7) |
8 ± 8.6 (n = 7)* |
3.5 ± 1.2 (n = 7) |
6 ± 3.4 (n = 7) |
2.6 ± 0.8 (n = 6) |
8.2 ± 3.9 (n = 6)* |
t1/2 (s) | 3.5 ± 0.8 (n = 7) |
9.6 ± 9.2 (n = 7)* |
4.4 ± 1.2 (n = 7) |
6.9 ± 3.4 (n = 7)* |
3.9 ± 0.9 (n = 6) |
10.1 ± 4 (n = 6)* |